Disruptive Wave

Disruptive Wave (originally DeMagic) is a recurring skill in the Dragon Quest series. Introduced in Dragon Quest III as a monster-exclusive attack, it nullifies all stat changes, such as those caused by buffs (Kabuff, Oomph) and debuffs (Kasap, Deceleratle).

It is typically known by major bosses and is practically required on final bosses, making the use of stat changing moves futile in such battles if one's luck is unrelentingly bad.

Dragon Quest IX

It is worth noting that Disruptive Wave acts slightly different in this installment as it now only affects the opposition. This makes debuffs viable against many bosses since they can't use the ability to clear them away.